Common Clinical Scenario: A 22-year-old woman presented for her annual exam. She had been smoking 15 cigarettes per day and was interested in quitting. Since she was healthy and not planning a pregnancy, she was started on varenicline and quit smoking 1 week later. She was initially seen weekly for brief counseling support sessions and to monitor for behavioral changes. She was continued on varenicline for 6 months and remained abstinent 1 year later.